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CD14 抗体 (APC)

This anti-CD14 antibody is a 小鼠 单克隆 antibody detecting CD14 in FACS. Suitable for 人 和 猴.
产品编号 ABIN238454
发货至: 中国

Quick Overview for CD14 抗体 (APC) (ABIN238454)

抗原

See all CD14 抗体
CD14

适用

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人, 猴

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD14 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)

克隆位点

MEM-18
  • 交叉反应 (详细)

    Species reactivity (tested):Human, Non-Human Primates

    纯化方法

    Size-exclusion chromatography

    免疫原

    A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria

    亚型

    IgG1
  • 应用备注

    Suitable for Flow Cytometry analysis of human blood cells using 10 m l reagent / 100 m l of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS, pH 7.4 with 15 mM sodium azide as preservative and 0.2 % (w/v) high-grade BSA (protease free) as a stabilizer

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody in the dark at 2-8 °C. Do Not freeze! Avoid prolonged exposure to light.
    Shelf Life: One year from despatch.

    有效期

    12 months
  • 抗原

    CD14

    别名

    CD14

    背景

    CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor, it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipo-polysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipo-polysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

    UniProt

    P08571

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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